Introduction: All Disease Categories


Major disease categories include cancer, musculoskeletal, cardiovascular, urogenital, respiratory, infectious, metabolic and gastrointestinal diseases. Drug manufacturers often look at diseases as categories in order to determine the most profitable targets for research.

Right Heart Failure


Decreased flow Tetralogy of Fallot Peripheral pulmonary artery stenosis (or stenoses) Unilateral absence or stenosis of pulmonary artery Vascular disease Pulmonary thromboembolic disease Primary pulmonary hypertension Hepatic cirrhosis and/or partial thrombosis Chemically induced (e.g., aminorex) Persistent fetal circulation Pulmonary arteritis Peripheral pulmonary artery stenosis Unilateral stenosis or absence of pulmonary artery Without pulmonary hypertension Pulmonic stenosis Tricuspid stenosis (nonrheumatic) Tricuspid regurgitation not associated with pulmonary hypertension Decreased right ventricular compliance Ebstein's anomaly Atrial myxoma


Associated with pulmonary venous hypertension (postcapillary) Cardiac disease (see previous Left Heart Failure) Pulmonary venous disease Mediastinal neoplasm or granuloma Mediastinitis and fibrosis Anomalous pulmonary venous return Congenital pulmonary venous stenosis Idiopathic pulmonary veno-occlusive disease Associated with pulmonary arterial hypertension (precapillary) Lung and pleural disease Chronic bronchitis, emphysema, and asthma Granulomatous disease (e.g., sarcoidosis) Pneumonia Fibrotic disease Neoplasm Chronic suppurative disease (e.g., bronchiectasis) Cystic fibrosis Collagen-vascular disease Other restrictive processes After lung resection Bronchopulmonary dysplasia Fibrothorax Chest wall deformity Kyphoscoliosis Thoracoplasty Congenital pulmonary hypoplasia (Down syndrome) Alveolar hypoventilation Neuromuscular Primary alveolar hypoventilation Obesity Sleep apnea syndrome High-altitude pulmonary hypertension Intracardiac disease Increased flow associated with large left-to-right shunt Patent ductus arteriosus Atrial septal defect Ventricular septal defect Sinus of Valsalva aneurysm


Left Heart Failure



Acute rheumatic fever Traumatic heart disease Thyrotoxicosis Thiamine deficiency Anemia Arteriovenous fistula (e.g., Paget's disease) Neoplastic heart disease Toxic shock syndrome Pulmonary thromboembolism Postcardioversion Pregnancy Left atrial thrombus



Hypertensive heart disease Coronary artery disease Left ventricular diastolic dysfunction Acute myocardial infarction Aortic and mitral valvular disease Cardiomyopathy Pericardial disease Arrhythmias Congenital heart disease Endocarditis Cardiotoxic drugs (e.g., Adriamycin) Myocarditis